Product ID:ACETONITRILE 00170, A21SS30
MSDS Date:12/12/1998
FSC:NIIN:Submitter:N EN
Status Code:A
MSDS Number: CJRHY

Emergency Phone: (800)424-9300

Info Phone: 201-796-7100

Cage: 1B464

Telephone: 201-796-7100

Cage: 1B464

(ORAL, RAT) 2730 MG/KG

CAS: 75-05-8

RTECS: AL7700000

OSHA PEL 70 MG/M3;40 PPM

ACGIH TLV: 67 MG/M3;40 PPM

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

LD50 LC50 Mixture:SEE INGREDIENT 1
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:EYE: MAY CAUSE MODERATE EYE IRRIT.
VAPS MAY CAUSE EYE IRRIT. SKIN: MAY BE HARMFUL IF ABSORBED THRU
SKIN. MAY BE METABOLIZED TO CYANIDE WHICH IN TURN ACTS BY
INHIBITING CYTOCHROME OXIDASE IMPAIRING CEL LULAR RESPIRATION.
INGEST: MAY CAUSE IRRIT OF DIGESTIVE TRACT. MAY CAUSE EFTS SIMILAR
TO THOSE FOR INHAL EXPOS. INHAL: HARMFUL IF INHALED. INHAL OF HIGH
CONCS MAY CAUSE CNS EFTS CHARACTERIZED BY HDCH, DIZZ, UNCON &
COMA. MAY CAUSE LIVER & KIDNEY DMG. VAPS MAY CAUSE DIZZ OR
SUFFOCATION. MAY CAUSE NAUS, DIZZ & HDCH. INHAL MAY LEAD TO DIZZ,
WEAK & DROW, LEADING TO STUPOR, UNCON & EVEN DEATH. INHAL MA Y LEAD
TO (EFTS OF OVEREXP)
Effects of Overexposure:HLTH HAZ: HEMATEMESIS, CONVULSIONS, CHOCK, COMA
& POSSIBLE DEATH. CHRONIC: CHRONIC INHAL & INGEST MAY CAUSE EFTS
SIMILAR TO THOSE OF ACUTE INHAL & INGEST. MAY BE METABOLIZED TO
CYANIDE WHICH IN TURN A CTS BY INHIBITING CYTOCHROME OXIDASE
IMPAIRING CELLULAR RESPIRATION. ANIMAL STUDIES HAVE REPORTED THAT
FETAL EFTS/ABNORMALITIES MAY OCCUR WHEN MATERNAL TOXICITY IS SEEN.

First Aid:EYES: FLUSH W/PLENTY OF WATER FOR AT LEAST 15 MIN, OCCASNLY
LIFTING UPPER & LOWER LIDS. GET MED AID IMMED. SKIN: GET MED AID
IMMED. FLUSH SKIN W/PLENTY OF SOAP & WATER FOR AT LEAST 15 MIN
WHILE REMOV ING CONTAM CLTHG & SHOES. INGEST: IF VICTIM CONSCIOUS &
ALERT, GIVE 2-4 CUPFULS OF MILK OR WATER. NEVER GIVE ANYTHING BY
MOUTH TO UNCON PERSON. GET MED AID IMMED. INHAL: GET MED AID
IMMED. REMOVE FRO M EXPOS TO FRESH AIR IMMED. IF BRTHG IS DFCLT,
GIVE OXYG. NOTES TO MD: EXPOS SHOULD BE TREATED AS CYANIDE
POISONING. EFTS MAY BE DELAYED. ANTIDOTE: ALWAYS HAVE CYANIDE
ANTIDOTE KIT ON HAND WHEN WORING W/CYANIDE CMPDS. GET MED ADVICE
TO USE.

Flash Point:=6.C, 42.8F
Autoignition Temp:=524.C, 975.2F
Lower Limits:4.4%
Upper Limits:16.0%
Extinguishing Media:SM FIRES:USE DRY CHEM, CO*2, WATER
SPRAY/ALCOHOL-RESIST FOAM. USE WATER SPRAY TO COOL FIRE-EXPOS
CNTNRS. WATER MAY BE INEFFECTIVE. DO NOT USE STRAIGHT STREAMS OF
WATER. LG (SUPDAT)
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT . NFPA RATING: HEALTH-2; FLAMMABILITY-3; REACTIVITY-0.
Unusual Fire/Explosion Hazard:CNTNRS CAN BUILD UP PRESS IF EXPOS TO
HEAT &/OR FIRE. VAPS MAY FORM EXPLO MIX W/AIR. VAPS CAN TRAVEL TO
IGNIT SOURCE & FLASH BACK. COMBUST GENERATES TOX FUMES. USE WATER
SPRAY TO KEEP FIRE-EXPOS CNTNR S COOL. FLAM LIQ. VAPS MAY BE
HVR/AIR. THEY CAN SPREAD ALONG GROUND & COLLECT IN LOW/CONFINED
AREAS. CNTNRS MAY (SUPDAT)

Spill Release Procedures:USE PROPER PERSONAL PROTECTIVE EQUIPMENT.
AVOID RUNOFF INTO STORM SEWERS AND DITCHES WHICH LEAD TO WATERWAYS.
REMOVE ALL SOURCES OF IGNITION. ABSORB SPILL USING AN ABSORBENT,
NON-COMBUSTIBLE MATERIAL SUCH AS EARTH, SAND OR VERMICULITE. A
VAPOR SUPPRESSING FOAM MAY BE USED TO REDUCE VAPORS. WATER SPRAY
MAY REDUCE VAPOR BUT MAY NOT PREVENT IGNITION IN CLOSED SPACES.

Handling and Storage Precautions:KEEP AWAY FROM HEAT, SPKS & FLAME.
KEEP AWAY FROM SOURCES OF IGNIT. STORE IN TIGHTLY CLOSED CNTNR.
KEEP FROM CNTCT W/OXIDIZING MATLS. STORE IN COOL, DRY, WELL-VENTD
AREA AWAY FROM INCOMPAT SUBSTANCES. WASH THOROUGHLY AFTER HNDLG.
REMOVE CONTAM CLTHG & WASH BEFORE USE. USE ONLY IN WELL VENTD AREA.
Other Precautions:GROUND & BOND CNTNRS WHEN TRANSFERRING MATL. AVOID
CNTCT W/EYES, SKIN & CLTHG. EMPTY CNTNRS RETAIN PROD RESIDUE (LIQ
&/OR VAP) & CAN BE DANGEROUS. KEEP CNTNR TIGHTLY CLSD. AVOID CNTCT
W/HEAT, SPKS & F LAME. DO NOT INGEST/INHALE. DO NOT PRESSURIZE,
CUT, WELD, BRAZE, SOLDER, DRILL, GRIND/EXPOSE EMPTY C NTNRS TO
(SUPDAT)

Respiratory Protection:FOLLOW THE OSHA RESPIRATOR REGULATIONS FOUND IN
29 CFR 1910.134 OR EUROPEAN STANDARD EN 149. ALWAYS USE A NIOSH OR
EUROPEAN STANDARD EN 149 APPROVED RESPIRATOR WHEN NECESSARY.
Ventilation:USE ADEQ GEN/LOC EXHST VENT TO KEEP AIRBORNE CONCS BELOW
PEL. ACETONITRILE: EXPOS LIMS: ACGIH-40PPM; 67 MG/M3; 60PPM STEL;
101 MG/M3 STEL. NIOSH-20PPM (SUPDAT)
Protective Gloves:IMPERVIOUS GLOVES .
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH AND DELUGE SHOWER .
WEAR APPROPRIATE PROTECTIVE CLOTHING TO PREVENT SKIN EXPOSURE.
Supplemental Safety and Health
OTHER PRECS:HEAT, SPKS/OPEN FLAME. EXTING MEDIA:FIRES:USE DRY CHEM,
CO*2, ALCOHOL-RESIST FOAM/WATER SPRAY. COOL CNTNRS W/FLOODING QTYS
OF WATER UNTIL WELL AFTER FIRE IS OUT. EXPLO HAZ:MAY EXPLODE WHEN
HEATED. VENT:TWA; 34MG/M3 TWA; 500PPM IDLH. OSHA-40PPM TWA; 70
MG/M3 TWA. OSHA VACATED PELS:40PPM TWA; 70MG/M3 TWA.

Melt/Freeze Pt:=-50.C, -58.F
Decomp Temp:Decomp Text:NOT AVAILABLE
Vapor Pres:73 MM HG
Vapor Density:1.4(AIR=1)
Spec Gravity:0.7810
pH:NOT AVAILABLE
Viscosity:0.36 CP 20 DEG
Solubility in Water:SOLUBLE
Appearance and Odor:CLEAR, COLORLESS LIQUID; SWEETISH ODOR - AROMATIC
ODOR.

Stability Indicator/Materials to Avoid:YES
CHLORINE FLUORIDE, FLUORINE, 2-CYANO-2-PROPYL NITRATE, DINITROGEN
TETRAOXIDE, INDIUM, DIPHENYL SULFOXIDE, TRICHLOROSILANE, N-FLUORO
CMPDS, IRON (III) PERCHLORATE, LANTHANIDE, NITRIC ACID, PERCHLORIC
ACID, SULFURIC ACID, SUL
Stability Condition to Avoid:STABLE UNDER NORMAL TEMPERATURES AND
PRESSURES. AVOID INCOMPATIBLE MATERIALS, IGNITION SOURCES.
Hazardous Decomposition Products:HYDROGEN CYANIDE, NITROGEN OXIDES,
CARBON MONOXIDE, CARBON DIOXIDE.

Waste Disposal Methods:DISPOSE OF IN A MANNER CONSISTENT WITH FEDERAL,
STATE AND LOCAL REGULATIONS. RCRA D-SERIES MAXIMUM CONCENTRATION OF
CONTAMINANTS: NONE LISTED. RCRA D-SERIES CHRONIC TOXICITY REFERENCE
LEVELS: NONE LIS TED. RCRA F-SERIES: NONE LISTED. RCRA P-SERIES:
NONE LISTED. RCRA U-SERIES: CAS #75-05-8: WASTE #U00 3 (IGNITABLE
WASTE; TOXIC WASTE).

Toxicological Information:CAS #75-05-8, RTECS #AL7700000. LD50/LC50 -
INHAL, MOUSE: LC50=2693 PPM/1H; INHAL, RABBIT: LC50=2828 PPM/4H;
INHAL, RAT: LC50=7551 PPM/8H; ORAL, MOUSE: LD50=269 MG/KG; ORAL,
RABBIT: LD50=50 MG/KG; ORA L, RAT: LD50=2730 MG/KG; SKIN,
RABBIT:LD50=1250 MG/KG; CARCINOGENICITY - ACGIH: A4 - NOT
CLASSIFIABLE AS HUMAN CARCIN. EPIDEMIOLOGY - NO INFO AVAIL.
TETRAGENICITY - EMBRYO OR FETUS: STUNTED FETUS, IHL -HAMSTER
TCLO=8000 PPM/1H. SPECIFIC DEVELOPMENTAL ABNORMS: MUSCULOSKELETAL,
ORL-HAMSTER TCLO=300 MG/KG. REPRO EFTS - FERTILITY:
POST-IMPLANTATION MORTALITY, ORL-HAMSTER TDLO=400 MG/KG &
IHL-HAMSTER TC LO=5000 PPM/1H. (OTHER INFO)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:EXOTOXICITY: FATHEAD MINNOW (HARD WATER) TLM=1150 PPM/24H.
ENVIRONMENTAL FATE: NO INFO REPORTED. PHYSICAL/CHEMICAL: NO INFO
AVAIL. OTHER: NONE. OTHER INFO: ADVICE IMMED (SHOW LABEL WHERE
POSS). WGK (W ATER DANGER/PROT) CAS #75-05-8: 2. CANADA: CAS
#75-05-8 IS LISTED ON CANADA'S DSL/NDSL LIST, HAS A WHMIS
CLASSIFICATION OF B2, D1B, D2B. IT IS NOT LISTED ON CANADA'S INGRED
DISCLOSURE LIST. EXPOS LIMS : CAS #75-05-8: OEL-ARAB REPUBLIC OF
EGYPT:TWA 40 PPM (70 MG/M3); SKIN OEL-AUSTRALIA: TWA 40 PPM (70
MG/M3); STEL 60 PPM; SKIN OEL-AUSTRIA; TWA 40 PPM (70 MG/M3)
OEL-BELGIUM:TWA 40 PPM (67 MG/M3); STE L 60 PPM (10 MG/M3);
(TRANSPORT INFO)

Transport Information:SHIPPING NAME - US DOT: ACETONITRILE; IATA: NO
INFO AVAIL; RID/ADR: NO INFO AVAIL. IMO: NO INFO AVAIL.
ACETONITRILE. HAZ CLASS - US DOT: 3; IMO: 3(6.1). UN NUMBER: US
DOT: UN1648; IMO: UN1648. PACKING GROUP: US DOT: II; IMO: II.
ADDNL INFO: IMO: FLASHPOINT 6C. ECOLOGICAL INFO: SKIN
OEL-DENMARK:TWA 40 PPM (70 MG/M3); STEL 60 PPM (10 MG/M3);
OEL-FINLAND: TWA 40 PPM (70 MG/M3); STEL 60 PPM (10 MG/M3) ;
OEL-FRANCE: TWA 50 MG/M3; STEL 100 MG/M3; SKIN JAN9 OEL-THE
NETHERLANDS: TWA 40 PPM (70 MG/M3) OEL-THE PHILIPPINES: TWA 40 PPM
(70 MG/M3) OEL-RUSSIA: STEL 10 MG/M3; OEL-SWITZERLAND: TWA 40 PPM
(70 M G/M3); STEL 80 PPM; (STATE REG INFO)

SARA Title III Information:CAS #75-05-8: SARA SECTION 302(RQ): FINAL
RQ=5000 LBS (2270 KG). SECTION 302(TPQ): NONE OF CHEMICALS IN
PRODUCT HAVE TPQ. SARA CODES: ACUTE, CHRONIC, FLAMMABLE. SECTION
313: MATERIAL CONTAINS ACETONIT RILE (CAS #75-05-8, 99%) WHICH IS
SUBJECT TO REPORTING REQS OF SECTION 313 OF SARA TITLE III & 40 CFR
PART 373.
Federal Regulatory Information:CAS #75-05-8: TSCA: LISTED ON TSCA
INVENTORY. HLTH & SFTY REPORTING LIST: EFTIVE DATE: OCT 4, 1982;
SUNSET DATE: OCT 4, 1992. CHEM TEST RULES: NONE OF CHEMS IN PROD
UNDER CHEM TEST RULE. SECTION 12B: NONE OF CHEMS LISTED UNDER TSCA
SECTION 12B. TSCA SIGNIFICANT NEW USE RULE: NONE OF CHEMS IN MATL
HAVE SNUR UNDER TSCA. CLEAN AIR ACT: LISTED AS HAZ AIR POLLUTANT
(HAP). MATL DOES NOT CNTN ANY CLASS 1 OR CLASS 2 OZONE DEPLETORS.
CLEAN WATER ACT: NONE OF CHEMS IN PROD LISTED AS HAZ SUBSTANCES
UNDER C WA. NONE OF CHEMS LISTED AS PRIORITY OR TOX POLLUTANTS
UNDER CWA. NONE CONSIDERED HIGHLY HAZ BY OSHA.
EUROPEAN/INTERNATIONAL (OTHER INFO)
State Regulatory Information:CAS #75-05-8 CAN BE FOUND ON FOLLOWING
STATE RIGHT TO KNOW LISTS: CALIFORNIA, NEW JERSEY, FLORIDA,
PENNSYLVANIA, MINNESOTA, MASSACHUSETTS. CALIFORNIA NO SIGNIFICANT
RISK LEVEL: NONE OF CHEMS IN THIS P ROD ARE LISTED. TRANSPORT INFO:
SKIN OEL-TURKEY: TWA 40 PPM (70 MG/M3) OEL-UNITED KINGDOM:TWA 40
PPM (70 MG/M3); STEL 60 PPM; OEL IN BULGARIA, COLOMBIA, JORDAN,
KOREA CHECK ACGIH. TLV OEL IN NEW ZEALA ND, SINGAPORE, VIETNAM
CHECK ACGIH TLV.